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Cluster headache - Treatment

Alternative Names

Histamine headache; Headache - histamine; Migrainous neuralgia; Headache - cluster

Treatment:

Treatment does not cure cluster headaches. The goal of treatment is to relieve symptoms. The headaches may go away on their own, or you may need treatment to prevent them.

Smoking, alcohol use, specific foods, and other factors that seem to trigger cluster headaches should be avoided. A headache diary can help you identify your headache triggers. When you get a headache, write down the day and time the pain began. The diary should include notes about what you ate and drank in the last 24 hours, how much you slept and when, and what was going on in your life immediately before the pain started. For example, were you under any unusual stress? Also include information about how long the headache lasted, and what made it stop.

Treatment for cluster headaches involves:

  • Methods to treat the pain when it happens
  • Medicines to prevent the headaches

Your doctor may recommend the following treatments for when the headaches occurs:

  • Several weeks of anti-inflammatory (steroid) medicines such as prednisone -- starting with a high dose, then gradually decreased
  • Breathing in 100% (pure) oxygen -- often relieves cluster headache for some people, particularly for frequent cluster headaches that occur at night

A combination of medicines may be needed to control headache symptoms. Because each person responds differently to medicine, your doctor may have you try several medications before deciding which works best for you.

Painkillers do not usually relieve the pain from cluster headaches. Generally, they take too long to work.

Medicines for preventing cluster headaches may include:

  • Ergot preparations
  • Methysergide maleate

These drugs may have severe side effects. Patients should call their doctor if they have chest pain, numbness or tingling in the fingers or toes, changes in heart rate, or any other unusual symptoms while taking these medicines.

The following medications may also be used to treat or prevent headache symptoms:

  • Antihistamines
  • Indomethacin
  • Lithium carbonate
  • Calcium channel blockers
  • Propranolol
  • Amitriptyline
  • Verapamil
  • Cyproheptadine

In rare cases, surgery on certain nerve cells near the brain may be recommended if medications do not work.

Expectations (prognosis):

Cluster headaches are not life-threatening and usually cause no permanent structural changes. However, they are chronic and may be painful enough to interfere with work or lifestyle. Occasionally, the pain may be so severe that some people may consider self harm. Side effects of medications or surgery may be severe.

Complications:

  • Headaches that interfere with daily activities
  • Horner syndrome
  • Side effects of medications
  • Complications due to surgery to treat the headaches, including:
    • Permanent muscle weakness in the face or head
    • Decreased sensation in parts of the face or head

Calling your health care provider:

Call for an appointment with your health care provider if cluster headaches do not respond to treatment, if headaches disturb sleep, if they happen whenever you are active, or are accompanied by other symptoms.

Emergency symptoms include drowsiness, vision changes, changes in movement or sensation, seizures, changes in alertness, and nausea or vomiting.

  • Reviewed last on: 6/19/2008
  • Daniel B. Hoch, PhD, MD, Assistant Professor of Neurology, Harvard Medical School, Department of Neurology, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Silberstein SD, Young WB. Headache and Facial Pain. In: Goetz, CG. Textbook of Clinical Neurology. 3nd ed. St. Louis, Mo: WB Saunders; 2007: chap. 53.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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