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Drug allergies - Symptom

Alternative Names

Allergic reaction - drug (medication)

Symptoms:

  • Anaphylaxis, or severe allergic reaction (see below)
  • Hives (a less common type of rash)
  • Itching of the skin or eyes (common)
  • Skin rash (common)
  • Swelling of the lips, tongue, or face
  • Wheezing

Symptoms of anaphylaxis include:

Signs and tests:

An examination of the skin and face may show hives, rash, or angioedema (swelling of the lips, face, or tongue). Decreased blood pressure, wheezing, and other signs may indicate an anaphylactic reaction.

Skin testing may confirm allergy to penicillin-type medications. Testing may be ineffective (or in some cases, dangerous) for other medications. A history of allergic-type reaction after use of a medication is often considered proof enough of drug allergy -- no further testing is required. The same applies to other substances that are not considered drugs but are used in hospitals, such as x-ray contrast dyes.

  • Reviewed last on: 8/6/2008
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Stuart I. Henochowicz, MD, FACP, Associate Clinical Professor of Medicine, Division of Allergy, Immunology, and Rheumatology, Georgetown University Medical School. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Adkinson NF Jr. Drug Allergy. In Adkinson NF Jr., Yunginger JW, Busse WW, Bochner BS, Holgate ST, eds. Middleton's Allergy: Principles and Practice. 6th ed. Philadelphia, Pa; Mosby Elsevier; 2003: chap 92.

Grammer LC. Drug Allergy. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 275.

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