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Lamellar ichthyosis - Treatment

Treatment:

Moisturizers containing urea, ammonium lactate, or other alpha-hydroxy acids may help. Also, retinoid medications such as tazarotene may be used on the skin (topically).

Gene therapy to correct the genetic defect may be possible in the future.

Complications:

When the collodian membrane is shed, babies are at risk for infection.

Later in life, eye problems may occur because the eyes cannot close completely.

  • Reviewed last on: 10/10/2010
  • Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine. Also reviewed by Kevin Berman, MD, PhD, Atlanta Center for Dermatologic Disease, Atlanta, GA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Morelli JG. Disorders of keratinization. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 657.

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