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Avoid known allergens. Any person experiencing an allergic reaction should be monitored, although monitoring may be done at home in mild cases.
Occasionally, people who have a history of drug allergies may safely be given the offending medication after pretreatment with corticosteroids (prednisone) and antihistamines (diphenhydramine).
People who have a history of allergy to insect bites/stings should be instructed to carry (and use) an emergency kit consisting of injectable epinephrine and chewable antihistamine. They should also wear a Medic-Alert or similar bracelet/necklace stating their allergy.
The diagnosis and management of anaphylaxis: an updated practice parameter. J Allergy Clin Immunol . 2005 Mar;115(3 Suppl):S483-523.
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