Symptoms:

• Fever
• General ill feeling
• Itching of the skin
• Joint aches
• Multiple skin lesions:
  • Start quickly and may return
  • May spread
  • May appear as a nodule, papule, or macule
  • Central lesion surrounded by pale red rings, also called a "target", "iris", or "bulls-eye"
  • May have vesicles and blisters of various sizes (bullae)
  • Located on the upper body, legs, arms, palms, hands, or feet
  • May involve the face or lips
  • Usually symmetrical

Other symptoms that may occur with this disease:

• Bloodshot eyes
• Dry eyes
• Eye burning, itching, and discharge
• Eye pain
• Mouth sores
• Vision abnormalities

Signs and tests:

The diagnosis is based mainly on the appearance of the skin lesion, especially if there is a history of risk factors or related diseases.

Tests may include:

• Nikolsky's sign
• Skin lesion biopsy and microscopic examination of the tissue