Because acanthosis nigricans itself usually only causes changes to the appearance of the skin, no particular treatment is needed.
It is important, however, to attempt to treat any underlying medical problem that may be causing these skin changes.
Acanthosis nigricans often fades if the cause can be found and treated.
Call your physician if you develop areas of thick, dark, velvety skin.
Morelli JG. Diseases of the Epidermis. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap. 656.