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Lichen planus - Overview

Definition of Lichen planus:

Lichen planus is a disease in which there is an itchy rash on the skin or in the mouth.

Causes, incidence, and risk factors:

The exact cause of lichen planus is unknown. However, it is likely to be related to an allergic or immune reaction.

Risks include:

  • Exposure to medications, dyes, and other chemical substances (including gold, antibiotics, arsenic, iodides, chloroquine, quinacrine, quinide, phenothiazines, and diuretics)
  • Disorders such as hepatitis C

Lichen planus generally affects middle-aged adults. It is less common in children.

  • Reviewed last on: 10/10/2010
  • Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine. Also reviewed by Kevin Berman, MD, PhD, Atlanta Center for Dermatologic Disease, Atlanta, GA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Habif, Thomas P. Clinical Dermatology. 5th ed. Philadelphia, Pa: Mosby Elsevier;2009:pp 320-326.

Mirowski GW, Mark LA. Oral disease and oral-cutaneous manifestations of gastrointestinal and liver disease. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 9th ed. Philadelphia, Pa: Saunders Elseiver;2010:chap 22.

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