The symptoms may include:
In some cases, a biopsy of the skin lesion can identify the fungus. On the other hand, erythema nodosum and erythema multiforme are inflammatory reactions and usually do not have fungus in them. A urine test may help detect the fungus in some cases.
Kauffman CA. Histoplasmosis. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 353.