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Erythema nodosum is an inflammatory disorder that is characterized by tender, red nodules under the skin.
In about half of cases, the exact cause of erythema nodosum is unknown. Some cases may be associated with the following:
Other associated disorders include leukemia, lymphoma, sarcoidosis, rheumatic fever, Bechet's disease, and ulcerative colitis.
The condition is more common in women than it is in men.
Schwartz RA, Nervi SJ. Erythema nodosum: a sign of systemic disease. Am Fam Physician. 2007;75(5):695-700.
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