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Cancer - vulva - Treatment

Alternative Names

Cancer - perineum

Treatment:

Imiquimod 5% cream may be used to treat vulvar intraepithelial neoplasia (VIN).

Treatment involves surgery to remove the cancer cells. If the tumor is large (more than 2 cm) or has grown deeply into the skin, the lymph nodes in the groin area may also be removed.

Radiation, with or without chemotherapy, may be used to treat advanced tumors or vulvar cancer that comes back.

Support Groups:

You can ease the stress of illness by joining a support group whose members share common experiences and problems. See cancer - support group.

Expectations (prognosis):

Most women with vulvar cancer who are diagnosed and treated at an early stage do well. However, a woman's outcome depends on:

  • The size of the tumor
  • The type of vulvar cancer
  • Whether the cancer has spread

The cancer commonly comes back at or near the site of the original tumor.

Complications:

Complications may include:

  • Spread of the cancer to other areas of the body
  • Side effects of radiation, surgery, or chemotherapy

Calling your health care provider:

Call your health care provider if you have any of these symptoms for more than 2 weeks:

  • Local irritation
  • Skin color change
  • Sore on the vulva
  • Reviewed last on: 1/31/2010
  • Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Zhingran A, Russell AH, Seiden MV, et al. Cancers of the cervix, vulva, and vagina. In: Abeloff MD, Armitage JO, Niederhuber JE, Kastan MB, McKenna WG, eds. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 91.

Kumar S, Shah JP, Bryant CS, et al. A comparison of younger vs older women with vulvar cancer in the United States. Am J Obstet Gynecol. 2009;200:e52-e55.

van Seters M, van Beurden M, ten Kate FJ, Beckmann I, Ewing PC, Eijkemans MJ, et al. Treatment of vulvar intraepithelial neoplasia with topical imiquimod. N Engl J Med. 2008;358:1465-1473.

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