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Dysfunctional uterine bleeding (DUB)

Definition:

Dysfunctional uterine bleeding (DUB) is abnormal vaginal bleeding not due to a physical (anatomical) cause that occurs in women in their reproductive years (who have previously started menstruation and not reached menopause).

Alternative Names:

Anovulatory bleeding; Bleeding - dysfunctional uterine; DUB

Causes, incidence, and risk factors:

Dysfunctional uterine bleeding (DUB) is diagnosed after all other causes of abnormal uterine bleeding are ruled out. This includes infection, tumors, disease, early pregnancy disorders, or structure problems.

DUB may be caused by an imbalance of one of the hormones related to ovulation (estrogen or progesterone).

Approximately 20% of cases of DUB occur in adolescents and 40% in women over 40. Obesity, excessive exercise, and emotional stress may be risk factors for DUB.

References:

Rakel P, ed. Conn ’s Current Therapy 2005 . 57th ed. Philadelphia, Pa: WB Saunders; 2005:1286-1288.

Stenchever A. Comprehensive Gynecology . 4th ed. St. Louis, Mo: Mosby; 2001:1082-1084.

Normal uterine anatomy (cut section)

Review Date: 5/15/2006
Reviewed By: Melanie N. Smith, M.D., Ph.D., Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, MA. Review provided by VeriMed Healthcare Network.

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