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Major depression with psychotic features - Treatment

Alternative Names

Psychotic depression; Delusional depression

Treatment:

Treatment usually involves antidepressant and antipsychotic medication. Patients sometimes take antipsychotics briefly. Electroconvulsive therapy is very effective for this condition, but it is generally used after medication.

Expectations (prognosis):

Having psychotic symptoms with depression is a serious condition. The depressive symptoms have a higher chance of returning than the psychotic symptoms. You may need to take medication for a long time to prevent depression from returning.

Ongoing treatment and monitoring offer the best chance of recovery and continuing to do well.

Complications:

Suicide or other self-harm is the most serious complication. You may need to stay in the hospital if you have thoughts of suicide. The safety of others must also be considered.

Calling your health care provider:

Call your health care provider if you or someone you know experiences depression or psychosis.

  • Reviewed last on: 2/6/2008
  • Christos Ballas, MD, Attending Psychiatrist, Hospital of the University of Pennsylvania, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

International early psychosis association writing group. International clinical practice guidelines for early psychosis. Br J Psychiatry, 2005;187:s120-s124.