Macular degeneration - Overview
Alternative Names
Age-related macular degeneration (AMD), AMD, Senile macular degeneration (SMD)
Definition of Macular degeneration:
Macular degeneration is an eye disorder that makes it difficult to see fine details. The condition affects the macula, the part of the retina responsible for central vision.
Causes, incidence, and risk factors:
Damage to the macula can gradually destroy central vision, which is used to read and see objects clearly.
Two types of macular degeneration (AMD) exist:
- Dry macular degeneration occurs when the macula becomes thin and dries out. Small yellow deposits, called drusen, form under the macula. As these drusen increase in size and number, they create a blurred spot in the central vision of the eye. Almost all people with macular degeneration have the dry form.
- Wet macular degeneration occurs when abnormal blood vessels grow under the macula and retina (this is called choroidal neovascularization). These vessels can leak blood and fluid, damaging the macula. Vision loss in the central vision can occur very quickly. Only about 10 percent of people with macular degeneration have this form, but it causes most of the vision loss associated with the condition.
Scientists arenā ' t sure what causes AMD. The disease is most common in people over 60, which is why it is often referred to as age-related macular degeneration.
Other risk factors are:
- Caucasian race
- Cigarette smoking
- Family history
- Female gender
- Obesity
- Reviewed last on: 8/4/2008
- Manju Subramanian, MD, Assistant Professor in Ophthalmology, Vitreoretinal Disease and Surgery, Boston University Eye Associates, Boston, MA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
References
Gohel PS, Mandava N, Olson JL, Durairaj VD. Age-related macular degeneration: an update on treatment.Am J Med. 2008 Apr;121(4):279-81.
Martidis A, Tennant MTS. Age-Related Macular Degeneration. In: Yanoff M, Duker JS, Augsburger JJ, et al, eds. Ophthalmology. 2nd ed. Philadelphia, Pa: Mosby Elsevier;2004:chap 125.