Symptoms:

One or both eyes may be affected.

They pupil may appear white or have white spots. A white glow in the eye is often seen in photographs taken with a flash. Instead of the typical "red eye" from the flash, the pupil may appear white or distorted.

Other symptoms can include:

• Crossed eyes
• Double vision
• Eyes that do not align
• Eye pain and redness
• Poor vision
• Differing iris colors in each eye

If the cancer has spread, bone pain and other symptoms may occur.

Signs and tests:

The doctor will perform a complete physical exam, including an eye exam. The following tests may be done:

• Eye exam with dilation of the pupil
• CT scan or MRI of the head
• Ultrasound of the eye (head and eye echoencephalogram)
• Bone marrow biopsy and cerebrospinal fluid examination in the case of more aggressive tumors