Definition of Cleft lip and palate:

Cleft lip and palate are birth defects that affect the upper lip and the roof of the mouth.

Causes, incidence, and risk factors:

There are many causes for of cleft lip and palate. Problems with genes passed down from one or both parents, drugs, viruses, or other toxins can all cause such birth defects. Cleft lip and palate may occur along with other syndromes or birth defects.

A cleft lip and palate can affect the appearance of one's face, and may lead to problems with feeding and speech, as well as ear infections. Problems may range from a small notch in the lip to a complete groove that runs into the roof of the mouth and nose. These features may occur separately or together.

Risk factors include a family history of cleft lip or palate and other birth defect. About 1 out of 2,500 people have a cleft palate.