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CSF leak - Overview

Alternative Names

Intracranial hypotension

Definition of CSF leak:

A CSF leak is an escape of the fluid that surrounds the brain and spinal cord.

Causes, incidence, and risk factors:

Any tear or hole in the membrane that surrounds the brain and spinal cord (dura) can allow the fluid that surrounds those organs to leak.

This fluid is called the cerebrospinal fluid (CSF). When it leaks out, the pressure around the brain and spinal cord drops.

Causes of leakage through the dura include:

  • Certain head, brain, or spinal surgeries
  • Head injury
  • Placement of tubes for epidural anesthesia or pain medications
  • Spinal tap (lumbar puncture)

Sometimes, no cause can be found. This is called a spontaneous CSF leak.

  • Reviewed last on: 9/26/2010
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Daniel B. Hoch, PhD, MD, Assistant Professor of Neurology, Harvard Medical School, Department of Neurology, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Biros MH, Heegaard WG. Head injury. In: Marx J, Hockberger RS, Walls RM, et al, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 7th ed. Philadelphia, Pa: Mosby Elsevier; 2009:chap 38.

DeAngelis LM. Tumors of the central nervous system and intracranial hypertension and hypotension. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 199.

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