Superior vena cava obstruction; Superior vena cava syndrome
SVC obstruction is a narrowing or blockage of the superior vena cava -- the second largest vein in the human body. The superior vena cava moves blood from the upper half of the body to the heart.
Superior vena cava (SVC) obstruction is a relatively rare condition.
Most often it is caused by cancer or a tumor in the mediastinum (the area of the chest under the breastbone and between the lungs).
The types of cancer that can lead to this condition include:
Superior vena cava obstruction can also be caused by noncancerous conditions that cause scarring. These conditions include:
Other causes of superior vena cava obstruction include:
Catheters placed in the large veins of the upper arm and neck may cause blood clots in the superior vena cava.
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Ugras-Rey S, Watson M. Selected oncologic emergencies. In: Marx JA, Hockberger RS, Walls RM, et al, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 7th ed. Philadelphia, Pa: Mosby Elsevier;2009:chap 121.
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