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Plummer-Vinson syndrome/esophageal web

• Overview
• Symptoms
• Treatment
• Prevention

Definition:

Plummer-Vinson syndrome consists of chronic iron deficiency anemia , difficulty swallowing , esophageal webs, and other, less common abnormalities. Esophageal webs are small, thin growths of tissue that partially block the esophagus (food pipe). They cause difficulty swallowing, and tend to be located in the middle or upper esophagus.

Alternative Names:

Paterson-Kelly syndrome; Sideropenic dysphagia

Causes, incidence, and risk factors:

The cause of Plummer-Vinson syndrome is unknown. Genetic factors and nutritional deficiencies may play a role. It is a rare disorder that is often connected with cancer of the esophagus and throat.

• Review Date: 10/13/2006
• Reviewed By: Jenifer K. Lehrer, MD, Department of Gastroenterology, Frankford-Torresdale Hospital, Jefferson Health System, Philadelphia, PA. Review provided by VeriMed Healthcare Network.

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