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Premature ovarian failure
Ovarian hypofunction is reduced function of the ovaries (including decreased production of hormones).
Ovarian hypofunction may be caused by genetic factors such as chromosome abnormalities, or it may occur with certain autoimmune disorders that disrupt normal ovarian function.
Chemotherapy and radiation therapy can also cause ovarian hypofunction.
Speroff L, Fritz MA. Clinical Gynecologic Endocrinology & Infertility, 7th ed. Lippincott Williams & Wilkins; 2004.
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