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Hartnup disorder - Treatment

Treatment:

Treatments include:

  • Avoiding sun exposure by wearing protective clothing and using a sunscreen of 15 factor or higher
  • Eating a high-protein diet
  • Taking supplements containing nicotinamide
  • Undergoing psychiatric treatment, such as the use of antidepressants or mood stabilizers, if mood swings or psychiatric problems occur

Expectations (prognosis):

Most people with this disorder can expect to live a normal life with no disability. Rarely, there have been reports of severe nervous system disease and even deaths in families with this disorder.

Complications:

There are usually no complications. When they occur, complications may include:

  • Changes in skin pigment that are permanent
  • Psychiatric problems
  • Rash
  • Uncoordinated movements

Nervous system symptoms are usually reversible. However, in rare cases they can be severe or life-threatening.

Calling your health care provider:

Call for an appointment with your health care provider if you have symptoms of this condition, especially if you have a family history of Hartnup disorder. Genetic counseling is recommended if you have a family history of this condition and are planning a pregnancy.

  • Reviewed last on: 8/7/2008
  • Diana Chambers, MS, EdD, Certified Genetics Counselor (ABMG), Charter Member of the ABGC, University of Tennessee, Memphis, TN. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Rezvani I. Defects in Metabolism of Amino Acids. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 85.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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