Treatment:

There is no specific treatment for Morquio syndrome. Researchers are currently testing a possible treatment involving enzyme replacement.

Symptoms are treated as they occur. A spinal fusion may prevent permanent spinal cord injury in persons whose neck bones are underdeveloped.

Support Groups:

National MPS Society --www.mpssociety.org

Expectations (prognosis):

Cognitive (thinking) function is usually normal in patients with Morquio syndrome.

Bone problems can lead to significant complications. For example, the small bones at the top of the neck may slip and damage the spinal cord, causing paralysis. Surgery to correct such problems should be done if possible.

Heart (cardiac) complications may lead to death.

Complications:

• Breathing problems
• Heart failure
• Spinal cord damage and possible paralysis
• Vision problems
• Walking problems related to abnormal curvature of the spine and other bone problems

Calling your health care provider:

Call your health care provider if symptoms of Morquio syndrome occur.