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Macroamylasemia - Overview

Definition of Macroamylasemia:

Macroamylasemia is the presence of an abnormal substance called macroamylase in the blood.

Causes, incidence, and risk factors:

Macroamylase is a molecule that consists of an enzyme, called amylase, which is attached to a protein. Because it is relatively large, macroamylase is filtered very slowly from the blood by the kidneys.

Macroamylasemia has been associated with:

  • Celiac disease
  • Lymphoma
  • HIV infection
  • Monoclonal gammopathy
  • Rheumatoid arthritis
  • Ulcerative colitis
  • Reviewed last on: 10/18/2008
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and George F. Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program, San Diego, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Owyang C. Pancreatitis. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 147.

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