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Macroamylasemia

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• Symptoms

Definition:

Macroamylasemia is the buildup of a molecule, called macroamylase, in the blood.

Causes, incidence, and risk factors:

Macroamylase is a molecule that consists of an enzyme , called amylase, bound to a protein. Because it is relatively large, macroamylase is filtered very slowly from the blood by the kidneys.

Macroamylasemia has been associated with:

• Celiac disease
• Ulcerative colitis
• Rheumatoid arthritis
• Lymphoma
• HIV infection
• Monoclonal gammopathy

• Review Date: 10/18/2006
• Reviewed By: Jenifer K. Lehrer, MD, Department of Gastroenterology, Frankford-Torresdale Hospital, Jefferson Health System, Philadelphia, PA. Review provided by VeriMed Healthcare Network.

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