One or both hands may be affected. The ring finger is affected most often, followed by the little, middle, and index fingers.
A small, painless nodule or lump develops in the tissue below the skin on the palm side of the hand. Over time, it thickens into a cord-like band.
It becomes difficult to extend or straighten the fingers. In severe cases, straightening them is impossible.
The health care will examine your hands. The physical examination of the palm will show thickened scar tissue and difficulty straightening the fingers.
Stretanski MF. Dupuytren contracture. In: Frontera, WR, Silver JK, Rizzo TD Jr, eds. Essentials of Physical Medicine and Rehabilitation. 2nd ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 25.
Gilpin D, Coleman S, Hall S, Houston A, Karrasch J, Jones N. Injectable collagenase Clostridium histolyticum: a new nonsurgical treatment for Dupuytren's disease. J Hand Surg Am. 2010 Dec;35(12):2027-38.e1. PubMed PMID: 21134613.
Hurst LC, Badalamente MA, Hentz VR, et al; CORD I Study Group. Injectable collagenase clostridium histolyticum for Dupuytren's contracture. N Engl J Med. 2009 Sep 3;361(10):968-79. PubMed PMID: 19726771.
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