Exercises, warm water baths, or splints may be helpful.
Surgery may be performed to release the contracture, depending on the severity of the condition. Normal movement of the fingers is usually restored by surgery followed by physical therapy exercises for the hand.
A newer treatment involves injecting a substance called collagenase into the scarred or fibrous tissue. Three injections are needed. You may have side effects such as swelling, pain, and itching. A more rare but severe side effect is rupture of the tendon.
The disorder progresses at an unpredictable rate. Surgical treatment can usually restore normal movement to the fingers. The disease can recur following surgery in up to half of cases within 10 years.
Worsening of the contracture may result in deformity and loss of function of the hand.
There is a risk of injury to blood vessels and nerves during surgery.
Call your health care provider if you have symptoms of this disorder.
Stretanski MF. Dupuytren contracture. In: Frontera, WR, Silver JK, Rizzo TD Jr, eds. Essentials of Physical Medicine and Rehabilitation. 2nd ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 25.
Gilpin D, Coleman S, Hall S, Houston A, Karrasch J, Jones N. Injectable collagenase Clostridium histolyticum: a new nonsurgical treatment for Dupuytren's disease. J Hand Surg Am. 2010 Dec;35(12):2027-38.e1. PubMed PMID: 21134613.
Hurst LC, Badalamente MA, Hentz VR, et al; CORD I Study Group. Injectable collagenase clostridium histolyticum for Dupuytren's contracture. N Engl J Med. 2009 Sep 3;361(10):968-79. PubMed PMID: 19726771.
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