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Arthritis

• Overview
• Symptoms
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Definition:

Arthritis is inflammation of one or more joints, which results in pain, swelling, and limited movement.

See also joint pain .

Alternative Names:

Joint inflammation

Causes, incidence, and risk factors:

Arthritis involves the breakdown of cartilage. Cartilage normally protects the joint, allowing for smooth movement. Cartilage also absorbs shock when pressure is placed on the joint, like when you walk. Without the usual amount of cartilage, the bones rub together, causing pain, swelling (inflammation), and stiffness.

You may have joint inflammation for a variety of reasons, including:

• Broken bone
• Infection (usually caused by bacteria or viruses)
• An autoimmune disease (the body attacks itself because the immune system believes a body part is foreign)
• General "wear and tear" on joints

Often, the inflammation goes away after the injury has healed, the disease is treated, or the infection has been cleared.

With some injuries and diseases, the inflammation does not go away or destruction results in long-term pain and deformity. When this happens, you have chronic arthritis. Osteoarthritis is the most common type and is more likely to occur as you age. You may feel it in any of your joints, but most commonly in your hips, knees or fingers. Risk factors for osteoarthritis include:

• Being overweight
• Previously injuring the affected joint
• Using the affected joint in a repetitive action that puts stress on the joint (baseball players, ballet dancers, and construction workers are all at risk)

Arthritis can occur in men and women of all ages. About 37 million people in America have arthritis of some kind, which is almost 1 out of every 7 people.

Other types or cause of arthritis include:

• Rheumatoid arthritis (in adults)
• Juvenile rheumatoid arthritis (in children)
• Systemic lupus erythematosus (SLE)
• Gout
• Scleroderma
• Psoriatic arthritis
• Ankylosing spondylitis
• Reiter's syndrome (reactive arthritis)
• Adult Still's disease
• Viral arthritis
• Gonococcal arthritis
• Other bacterial infections ( non-gonococcal bacterial arthritis )
• Tertiary Lyme disease (the late stage)
• Tuberculous arthritis
• Fungal infections such as blastomycosis

References:

Krishnan E. Reduction in long-term functional disability in rheumatoid arthritis from 1977 to 1998: a longitudinal study of 3035 patients. Am J Med . 2003; 115(5): 371-376.

Maini SR. Infliximab treatment of rheumatoid arthritis. Rheum Dis Clin North Am . 2004; 30(2): 329-347.

Marx J. Rosen’s Emergency Medicine: Concepts and Clinical Practice . 5th ed. St. Louis, Mo: Mosby; 2002:1583-1599.

Simon LS, Lipman AG, Jacox AK, etc. Pain in osteoarthritis, rheumatoid arthritis and juvenile chronic arthritis. 2nd ed. Glenview (IL): American Pain Society (APS); 2002.

• Review Date: 10/13/2005
• Reviewed By: Ariel D. Teitel, M.D., M.B.A., Chief, Division of Rheumatology, St.Vincent's Hospital, New York, NY. Review provided by VeriMed Healthcare Network.

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