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Lymphadenitis - Overview

Alternative Names

Lymph node infection; Lymph gland infection; Localized lymphadenopathy

Definition of Lymphadenitis:

Lymphadenitis is an infection of the lymph nodes (also called lymph glands). It is a common complication of certain bacterial infections.

Causes, incidence, and risk factors:

The lymph system is a network of organs, lymph nodes, lymph ducts, and lymph vessels (or channels) that produce and move a fluid called lymph from tissues to the bloodstream. For more information on this part of the body, see lymph system.

The lymph glands, or nodes, are small structures that filter the lymph fluid. There are many white blood cells in the lymph nodes to help fight infection.

Lymphadenitis occurs when the glands become enlarged by inflammation, usually in response to bacteria, viruses, or fungi. The swollen glands are usually found near the site of an underlying infection, tumor, or inflammation.

Lymphadenitis may occur after skin infections or other bacterial infections, particularly those due to streptococcus or staphylococcus. Sometimes it is caused by rare infections such as tuberculosis or cat scratch disease (Bartonella).

  • Reviewed last on: 5/30/2009
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Armitage JO. Approach to the patient with lymphadenopathy and splenomegaly. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier. 2007: chap 174.
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