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Glanzmann's disease - Overview

Alternative Names

Thrombasthenia

Definition of Glanzmann's disease:

Glanzmann� ' s disease is a rare disorder of blood platelets, which results in easy bruising and nosebleeds.

Causes, incidence, and risk factors:

Glanzmann� ' s disease is caused by lack of a protein required for platelets to clump together (aggregate) normally.

The condition is congenital, which means it is present from birth.

Reviewed last on: 3/2/2009
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

McMillan R. Hemorrhagic disorders: Abnormalities of platelet and vascular function. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 179.

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