Home > Medical Reference > Encyclopedia (English)
Toggle: English / Spanish
Do Not Remove This Text
Related Content
Hyperimmunoglobulin E syndrome - Symptom
Alternative Names
Job syndrome; Hyper IgE syndrome
Symptoms:
- Persistent skin abscesses and infection
- Recurrent pus in the sinus
- Eczema
- Bone and tooth defects, including fractures and late shedding of baby teeth
Signs and tests:
An eye exam may reveal signs of dry eye syndrome. A physical exam may show signs of osteomyelitis, curving of the spine (kyphoscoliosis), and recurrent sinus infections.
A chest x-ray may reveal lung abscesses.
Tests used to confirm a diagnosis include:
- Absolute eosinophil count
- CBC with blood differential
- Serum globulin electrophoresis to look for high blood IgE levels
Other tests that may be done:
- X-ray of the sinuses
- X-ray of the bones
- CT scan of the chest
- Cultures of infected site
- Reviewed last on: 7/25/2007
- Donald Accetta, MD, MPH, President, Allergy & Asthma Care, PC, Taunton, MA. Review provided by VeriMed Healthcare Network.
References
Cohen J, Powderly WG. Infectious Diseases. 2nd ed. New York, NY: Elsevier; 2004.
Hoffman R, Benz EJ, Shattil SS, et al. Hematology: Basic Principles and Practice. 4th ed. Orlando, Fl: Churchill Livingstone; 2005.
Email this Page
Print this Page