Hyperimmunoglobulin E syndrome - Treatment

Alternative Names

Job syndrome; Hyper IgE syndrome

Treatment:

There is no known cure for this condition. The goal of treatment is to control the infections. Medications include:

Antibiotics
Antifungal and antiviral medications (when appropriate)

Sometimes, surgery is needed to drain abscesses.

Gamma globulin given through a vein (IV) may help build up the immune system if you have severe infections.

Expectations (prognosis):

Job syndrome is a lifelong chronic condition. Each new infection requires treatment.

Complications:

Repeated infections
Sepsis

Calling your health care provider:

Call your health care provider if you have symptoms of Job syndrome.

Reviewed last on: 8/1/2011
John A. Daller, MD, PhD, Department of Surgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Genetics Home Reference (GHR). Job Syndrome. Feb 2008. Accessed Nov. 13, 2008.

Immune Deficiency Foundation. Immune Deficiency Foundation Patient & Family Handbook. Chapter 12: Hyper IgE Syndrome. 4th ed. 2007. Accessed Nov. 13, 2008.

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