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Congenital afibrinogenemia - Symptom

Symptoms:

Signs and tests:

If the health care provider suspects a bleeding disorder, laboratory tests can determine the type and extent. This disorder usually shows up in childhood, often at birth.

Tests include:

  • Bleeding time
  • Clotting time
  • Fibrinogen levels
  • Partial thromboplastin time (PTT)
  • Prothrombin time (PT)
  • Reptilase time
  • Thrombin time

All of these tests are abnormal in afibrinogenemia.

  • Reviewed last on: 3/2/2009
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Kessler C. Hemorrhagic disorders: Coagulation factor deficiencies. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 180.

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