Treatment:

To treat bleeding episodes or to prepare for surgery to treat other conditions, patients may receive:

• Cryoprecipitate (a blood product containing concentrated fibrinogen and other clotting factors) through a vein (transfusion)
• Fibrinogen (RiaSTAP)
• Plasma (the liquid portion of the blood containing clotting factors)

People with this condition should have the hepatitis B vaccine because transfusion increases the risk of hepatitis.

Expectations (prognosis):

Excess bleeding is common with this condition. These episodes may be severe, or even fatal. Bleeding in the brain is a leading cause of death in patients with this disorder.

Complications:

• Bleeding from the umbilical cord
• Bleeding from the mucus membranes
• Bleeding in the brain (intracranial bleeding)
• Clotting with treatment
• Development of antibodies (inhibitors) to fibrinogen with treatment
• Gastrointestinal bleeding
• Miscarriage

Calling your health care provider:

Call your health care provider or seek emergency care if you have excessive bleeding.

Tell your surgeon before you have surgery if you know or suspect you have a bleeding disorder.