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Malignant hyperthermia - Treatment

Alternative Names

Hyperthermia - malignant; Hyperpyrexia - malignant

Treatment:

For an episode of malignant hyperthermia, a cooling blanket can help reduce fever. The use of a drug called dantrolene during episodes of malignant hyperthermia has greatly reduced the number of deaths.

Fluids given by IV and mouth, as well as certain medications, are essential for maintaining kidney function during an acute episode.

Support Groups:

Malignant Hyperthermia Association of the United States - www.mhaus.org

Expectations (prognosis):

Repeated episodes or untreated episodes can cause kidney failure. Untreated episodes can be fatal.

Complications:

  • Rhabdomyolysis, a kidney injury caused by excess myoglobin
  • Renal failure
  • Myopathy (weak muscles) or muscular dystrophy
  • Death

Calling your health care provider:

If you know that you or a member of your family has had problems with general anesthesia, or if you know you have a family history of malignant hyperthermia, be sure to notify both the surgeon and the anesthesiologist before having any surgery.

  • Reviewed last on: 7/23/2008
  • A.D.A.M. Editorial Team: David Zieve, MD, MHA, Greg Juhn, MTPW, David R. Eltz. Previously reviewed by Chad Haldeman-Englert, MD, Division of Human Genetics, Children's Hospitalof Philadelphia, Philadelphia, PA. Review provided by VeriMed HealthcareNetwork (7/25/2007).

References

Vicario S. Heat illness. In: Marx J, ed. Rosen’s Emergency Medicine: Concepts and Clinical Practice. 6th ed. St. Louis, Mo: Mosby; 2006:chap 139.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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