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Herpes simplex - Treatment

Treatment:

Some cases are mild and may not need treatment.

People who have severe or prolonged cases, immune system problems, or frequent recurrences may need to take antiviral medications such as acyclovir (Zovirax), famciclovir (Famvir), and valacyclovir (Valtrex).

People who have more than 6 recurrences of genital herpes per year may need to continue taking antiviral medications to reduce recurrences.

Support Groups:

Support groups and dating services are available for people with genital herpes.

Expectations (prognosis):

The oral or genital lesions usually heal on their own in 7 to 10 days. The infection may be more severe and last longer in people who have a condition that weakens the immune system.

Once an infection occurs, the virus spreads to nerve cells and stays in the body for the rest of a person's life. It may come back from time to time and cause symptoms, or flares. Recurrences may be triggered by excess sunlight, fever, stress, acute illness, and medications or conditions that weaken the immune system (such as cancer, HIV/AIDS, or the use of corticosteroids).

Complications:

  • Meningitis
  • Encephalitis
  • Eczema herpetiform (widespread herpes across the skin)
  • Infection of the eye -- keratoconjunctivitis
  • Prolonged, severe infection in immunosuppressed individuals
  • Pneumonia
  • Infection of the trachea

Calling your health care provider:

Call your health care provider if you develop symptoms which appear to be herpes infection. There are many different conditions that can cause similar lesions (especially in the genital area).

If you have a history of herpes infection and develop similar lesions, tell your health care provider if they do not get better after 7 to 10 days, or if you have a condition that weakens your immune system.

  • Reviewed last on: 4/7/2008
  • A.D.A.M. Editorial Team: David Zieve, MD, MHA, Greg Juhn, MTPW, David R. Eltz, Kelli A. Stacy, ELS. Previously reviewed by Mark Levin, MD, Division of Infectious Disease, MacNeal Hospital, Berwyn, IL. Review provided by VeriMed Healthcare Network (6/8/2007).

References

Workowski KA, Berman SM. Sexually Transmitted Diseases Treatment Guidelines, 2006. MMWR Morb Mortal Wkly Rep. August 4, 2006;55(RR-11):1-94.

Stoopler ET. Oral herpetic infections (HSV 1-8). Dent Clin North Am. 2005 Jan;49(1):15-29, vii.

Mandell GL, Bennett JE, Dolin R. Principles and Practice of Infectious Diseases. 5th ed. Philadelphia, Pa: Churchill Livingstone; 2000.