Symptoms:

The symptoms of syphilis depend on the stage of the disease. Many people do not have symptoms.

In general, painless sores and swollen lymph nodes are symptoms of primary syphilis. Those with secondary syphilis may also have fever, fatigue, aches and pains, and loss of appetite, among other symptoms. Tertiary syphilis causes heart, brain, and nervous system problems.

For more information, see the article on the specific stage of syphilis.

Signs and tests:

Blood tests can be done to detect substances produced by the bacteria that causes syphilis. The older test is the VDRL test. Other blood tests may include RPR and FTA-ABS.