The skin infection is usually treated with an antifungal medicine called itraconazole. It is taken by mouth and continued for 2 to 4 weeks after the skin lesions have cleared. You may have to take the medicine for 3 to 6 months.
Fluconazole is used in patients who do not respond to itraconazole. Systemic or disseminated infection is often treated with amphotericin B, or sometimes itraconazole. Therapy for systemic disease can last up to 12 months.
With treatment, full recovery can be expected. Disseminated sporotrichosis is more difficult to treat and requires chemotherapy drugs. Disseminated sporotrichosis can be life-threatening for people with a compromised immune system.
In people with a normal immune system:
In people who are immunosuppressed:
Call for an appointment with your health care provider if you develop persistent skin lumps or skin ulcers. If you know that you have been exposed to vegetation, mention this to your health care provider.
Kauffman CA. Sporotrichosis. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 358.
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