Symptoms:

Congenital toxoplasmosis can damage the baby's eyes, nervous system, skin, and ears.

Symptoms include:

• Anemia
• Enlarged liver and spleen
• Eye damage from inflammation of the retina
• Jaundice
• Low birth weight
• Prematurity
• Skin rash (petechiae or ecchymosis) at birth

Signs and tests:

The physical examination may show signs of:

• Anemia
• Cerebral calcifications
• Chorioretinitis
• Hydrocephalus
• Lymphadenopathy
• Macrocephaly or microcephaly

Signs and symptoms that occur late in the disease include:

• Hearing loss
• Mental retardation
• Seizures
• Neurological problems
• Visual impairment

Prenatal tests include:

• Amniotic fluid testing and fetal blood testing
• Antibody titer
• Ultrasound of the abdomen

Postnatal diagnosis:

• Antibody studies on cord blood and cerebrospinal fluid
• CT scan of the brain
• MRI scan of the brain
• Neurological exams
• Standard eye exam
• TORCH screen