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Group B streptococcal septicemia of the newborn - Treatment

Treatment:

Treatment may involve one or more of the following:

  • Antibiotics given through a vein
  • Fluids given through a vein
  • Medicines to reverse shock
  • Medicines or procedures to correct blood clotting problems
  • Oxygen therapy
  • Breathing help

A complex therapy called extra-corporeal membrane oxygenation (ECMO) may be used in very severe cases.

Expectations (prognosis):

This disease can be deadly without early treatment.

Complications:

Possible complications include:

  • Disseminated intravascular coagulation (DIC) -- a serious disorder in which the proteins that control blood clotting are abnormally active
  • Hypoglycemia -- low blood sugar
  • Meningitis -- an infection that causes inflammation of the membranes covering the brain and spinal cord
  • Respiratory distress -- breathing stops

Calling your health care provider:

This disease is usually diagnosed shortly after birth, often while the baby is still in the hospital. However, if you have a newborn at home who shows signs of this condition, seek immediate emergency medical help or call the local emergency number (such as 911).

  • Reviewed last on: 10/8/2007
  • Deirdre O’Reilly, MD, MPH, Neonatologist, Division of Newborn Medicine, Children’s Hospital Boston and Instructor in Pediatrics, Harvard Medical School, Boston, Massachusetts. Review Provided by VeriMed Healthcare Network.

References

Mandell GL, Bennett JE, Dolin R. Principles and Practice of Infectious Diseases. 6th ed. London: Churchill Livingstone; 2005.

Schrag S, Gorwitz R, Fultz-Butts K, Schuchat A. Prevention of perinatal group B streptococcal disease. Morbidity and Mortality Weekly Report. 51(RR-11): 1–22, 2002.

Schrag S. Prevention of neonatal sepsis. Clin Perinatol. Sept 2005; 32(3): 601-15.

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