Definition of Pleurisy:

Pleurisy is inflammation of the lining of the lungs and chest (the pleura) that leads to chest pain (usually sharp) when you take a breath or cough.

Causes, incidence, and risk factors:

Pleurisy may develop when you have lung inflammation due to infections such as pneumonia or tuberculosis. This inflammation also causes the sharp chest pain of pleurisy.

It may also occur with:

• Asbestos-related disease
• Certain cancers
• Chest trauma
• Pulmonary embolus
• Rheumatoid arthritis
• Lupus

Symptoms:

The main symptom of pleurisy is pain in the chest. This pain often occurs when you take a deep breath in or out, or cough. Some people feel the pain in the shoulder.

Deep breathing, coughing, and chest movement makes the pain worse.

Pleurisy can cause fluid to collect inside the chest cavity. This can make breathing difficult and may cause the following symptoms:

• Bluish skin color (cyanosis)
• Coughing
• Shortness of breath
• Rapid breathing (tachypnea)

Signs and tests:

When you have pleurisy, the normally smooth surfaces lining the lung (the pleura) become rough. They rub together with each breath, and may produce a rough, grating sound called a "friction rub." Your health care provider can hear this sound with the stethoscope, or by placing an ear against your chest.

The health care provider may perform the following tests:

• CBC
• CT scan of the chest
• Thoracentesis
• Ultrasound of the chest
• X-ray of the chest

Treatment:

Treatment depends on what is causing the pleurisy. Bacterial infections are treated with antibiotics. Surgery may be needed to drain infected fluid from the lungs.

Viral infections normally run their course without medications. Patients often can control the pain of pleurisy with acetaminophen or anti-inflammatory drugs such as ibuprofen.

Expectations (prognosis):

Recovery depends on what is causing the pleurisy.

Complications:

• Breathing difficulty
• Collapsed lung due to thoracentesis
• Complications from the original illness

Calling your health care provider:

Call your health care provider if you have symptoms of pleurisy. If you have breathing difficulty or your skin turns blue, seek immediate medical care.

Prevention:

Early treatment of bacterial respiratory infections can prevent pleurisy.