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Treatment varies depending on:
In certain cases, surgery alone is enough. Often, though, other therapies are needed. Anticancer medications (chemotherapy) may be recommended if the tumor has spread. Radiation therapy may also be used.
High-dose chemotherapy, followed by autologous stem cell transplantation, is being studied for use in children with very high-risk tumors.
The outcome varies. In very young children with neuroblastoma, the tumor may go away on its own, without any treatment. Or, the tissues of the tumor may mature and develop into a non-cancerous (benign) tumor called a ganglioneuroma, which can be surgically removed. In other cases, the tumor spreads quickly.
Response to treatment also varies. Treatment is often successful if the cancer has not spread. If it has spread, neuroblastoma is much harder to cure. Younger children often do better than older children.
Tumors with certain genetic characteristics may be harder to cure.
Children treated for neuroblastoma may be at risk for getting a second, different cancer in the future.
Call your health care provider if your child has symptoms of neuroblastoma. Early diagnosis and treatment improves the chance of a good outcome.
Dome JS, Rodriguez-Galindo C, Spunt SL, Santana VM. Pediatric Solid Tumors. In: Abeloff MD, Armitage JO, Niederhuber JE, Kastan MB, McKenna WG, eds. Clinical Oncology. 4th ed. Philadelphia, Pa; Churchill Livingstone Elsevier; 2008:chap 99.
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