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Rhabdomyosarcoma - Treatment

Alternative Names

Soft tissue sarcoma; Alveolar rhabdomyosarcoma; Embryonal rhabdomyosarcoma; Sarcoma botryoides

Treatment:

The precise treatment depends on the site and type of rhabdomyosarcoma. This tumor is best treated at a center with experience treating rhabdomyosarcoma.

In general, surgery and radiation therapy are used to treat the primary site of the tumor, while chemotherapy is used to treat disease at all sites in the body.

Chemotherapy is an essential part of treatment to prevent further spread of the cancer. Many different chemotherapy drugs are active against rhabdomyosarcoma. Some of these drugs include:

  • Vincristine
  • Actinomycin-D
  • Cyclophosphamide (Cytoxan)
  • Doxorubicin (Adriamycin)
  • Melphalan
  • Ifosfamide
  • Etoposide
  • Topotecan

Support Groups:

The stress of illness can often be helped by joining a support group where members share common experiences and problems. See cancer - support group.

Expectations (prognosis):

While aggressive treatment is usually necessary, most children with rhabdomyosarcoma will achieve long-term survival. Cure depends on the specific type of tumor, its location, and the amount that it has spread.

Complications:

  • Complications from chemotherapy
  • Location in which surgery is not possible
  • Metastasis

Calling your health care provider:

Call your health care provider if your child has symptoms of rhabdomyosarcoma.

  • Reviewed last on: 3/21/2008
  • Stephen Grund, MD, PhD, Chief of Hematology/Oncology and Director of the George Bray Cancer Center at New Britain General Hospital, New Britain, CT. Review provided byVeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Skubitz KM, D'Adama DR. Sarcoma. Mayo Clin Proc.2007:82(11):1409-1432.

Maki RG. Pediatric sarcomas occurring in adults. J Surg Oncol. 2008:97(4):360-368.

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