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Gestational trophoblastic disease

• Overview
• Symptoms
• Treatment
• Prevention

Alternative Names:

Chorioblastoma; Choriocarcinoma; Trophoblastic tumor; Chorioepithelioma; Invasive/malignant mole; Gestational trophoblastic neoplasia

Symptoms:

A possible symptom is continued vaginal bleeding in a woman with a recent history of hydatidiform mole, abortion, or pregnancy.

Additional symptoms may include:

• Irregular vaginal bleeding
• Certain types of cysts on the ovaries
• Uneven swelling of the uterus
• Persistently high HCG (pregnancy hormone) levels (positive pregnancy test)
• Pain

Signs and tests:

A pelvic examination may reveal continued uterine enlargement or a tumor. These conditions may be felt within the genito-urinary tract.

Tests include:

• Quantitative serum HCG (blood test to confirm pregnancy)
• CT scan
• Chest x-ray

These signs and tests apply to women with a recent history of hydatidiform mole, abortion, or pregnancy.

• Review Date: 9/11/2006
• Reviewed By: Rita Nanda, M.D., Department of Medicine, Section of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL. Review provided by VeriMed Healthcare Network.

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