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Home > Medical Reference > Encyclopedia (English)

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Malignancy - Overview

Definition of Malignancy:

The term "malignancy" refers to cancerous cells that usually have the ability to spread, invade, and destroy tissue. Malignant cells tend to have fast, uncontrolled growth due to changes in their genetic makeup.

Malignant cells that are resistant to treatment may return after all detectable traces of them have been removed or destroyed.

  • Reviewed last on: 11/10/2008
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and James R. Mason, MD, Oncologist, Director, Blood and Marrow Transplantation Program and Stem Cell Processing Lab, Scripps Clinic, Torrey Pines, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Goldman L, Ausiello D. Cecil Textbook of Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:1345-1348.

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