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Hydrocodone and acetaminophen overdose - Treatment

Alternative Names

Lorcet overdose; Lortab overdose; Vicodin overdose

Home Treatment:

Seek immediate medical help. Do NOT make a person throw up unless told to do so by Poison Control or a health care professional.

Before Calling Emergency:

Determine the following:

  • Patient's age, weight, and condition
  • Name of the product (ingredients and strengths, if known)
  • Time it was swallowed
  • Amount swallowed
  • If the medication was prescribed for the patient

Poison Control, or a local emergency number:

The National Poison Control Center (1-800-222-1222) can be called from anywhere in the United States. This national hotline number will let you talk to experts in poisoning. They will give you further instructions.

This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.

See: Poison control center - emergency number

What to expect at the emergency room:

The health care provider will measure and monitor your vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated as appropriate. You may receive:

  • Activated charcoal
  • Artificial respiration
  • Fluids
  • Laxative
  • Medicine to lower acetaminophen levels in the blood (N-acetylcysteine)
  • Medicine to reverse the effect of the hydrocodone (narcotic antagonist)
  • Tube through the mouth into the stomach to wash out the stomach (gastric lavage)

Expectations (prognosis):

How well you do depends on the amount of poison swallowed and how quickly treatment is received. The faster you get medical help, the better the chance for recovery.

If you can receive medicines to reverse the overdose, you may get better within 1 - 4 days.

  • Reviewed last on: 1/23/2008
  • Eric Perez, MD, Department of Emergency Medicine, St. Luke’s-Roosevelt Hospital Center, New York, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.