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Kidney transplant - Overview

Alternative Names

Renal transplant; Transplant - kidney

Definition of Kidney transplant:

A kidney transplant is surgery to place a healthy kidney into a person with kidney failure.

Description:

Kidney transplants are one of the most common transplant operations in the United States.

One donated kidney is needed to replace the work previously done by your kidneys.

The donated kidney may be from:

  • Living related donor -- related to the person receiving the transplant, such as a parent, sibling, or child
  • Living unrelated donor -- such as a friend or spouse
  • Deceased donor -- a person who has recently died and who has no known chronic kidney disease

The healthy kidney is transported in cool salt water (saline) that preserves the organ for up to 48 hours. This gives the health care providers time to perform tests that match the donor's and recipient's blood and tissue before the operation.

PROCEDURE FOR A LIVING KIDNEY DONOR

If you are donating a kidney, you will be placed under general anesthesia before surgery. This means you will be asleep and pain-free. Usually, surgeons today can use small surgical cuts with laparoscopic techniques. See kidney removal for more information.

PROCEDURE FOR THE PERSON RECEIVING THE KIDNEY (RECIPIENT)

People receiving a kidney transplant are given general anesthesia before surgery. The surgeon makes a cut in the lower belly area.

  • Your surgeon places the new kidney inside your lower belly. The artery and vein of the new kidney are connected to the artery and vein in your pelvis. Your blood flows through the new kidney, which makes urine just like your own kidneys did when they were healthy. The tube that carries urine (ureter) is then attached to your bladder.
  • Your own kidneys are left in place, unless they are causing high blood pressure, infections, or are too large for your body. The wound is then closed.

Kidney transplant surgery takes about 3 hours. People with diabetes may also have a pancreas transplant done at the same time. This will usually add another 3 hours to the surgery.

See also: Pancreas transplant

Why the Procedure Is Performed:

Your doctor may recommend a kidney transplant if you have end-stage kidney disease. The most common cause of end-stage kidney disease in the U.S. is diabetes. However, there are many other causes.

A kidney transplant may NOT be done if you have:

  • Certain infections, such as TB or bone infections
  • Problems taking medications several times each day for the rest of your life
  • Heart, lung, or liver disease
  • Other life-threatening diseases
  • Recent history of cancer
  • Infections such as hepatitis
  • Smoking, alcohol or drug abuse, or other risky lifestyle habits
  • Reviewed last on: 6/13/2011
  • Scott Miller, MD, Urologist in private practice in Atlanta, Georgia. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Barry JM, Jordan ML, Conlin MJ. Renal transplantation. In: Wein AJ, ed. Campbell-Walsh Urology. 9th ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 40.

Kidney Disease: Improving Global Outcomes (KDIGO) Transplant Work Group. KDIGO clinical practice guideline for the care of kidney transplant recipients. Am J Transplant. 2009 Nov;9 Suppl 3:S1-155.

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