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Pancreas transplant - Risks

Alternative Names

Transplant - pancreas; Transplantation - pancreas

Risks:

The risks for any surgery are:

  • Bleeding
  • Breathing problems
  • Heart attack or stroke
  • Infection or abscess
  • Reactions to medications
  • Scar formation

The risks for pancreas transplant include:

  • Blood clots (deep venous thrombosis)
  • Clotting (thrombosis) of the arteries or veins of the new pancreas
  • Development of certain cancers after a few years
  • Inflammation of the pancreas (pancreatitis)
  • Leakage of fluid from the new pancreas where it attaches to the intestine or bladder
  • Rejection

The body's immune system considers the transplanted organ foreign, and fights it. To prevent rejection, organ transplant patients must take drugs (such as cyclosporine and corticosteroids) that weaken the body's immune response. This makes the person less able to fight infections and can cause other medical problems.

  • Reviewed last on: 5/4/2011
  • Shabir Bhimji, MD, PhD, Specializing in General Surgery, Cardiothoracic and Vascular Surgery, Midland, TX. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Lipshutz GS, Wilkinson AH. Pancreas-kidney and pancreas transplantation for the treatment of diabetes mellitus. Endocrinol Metab Clin North Am. 2007;36(4).

White SA, Shaw JA, Sutherland DE. Pancreas transplantation. Lancet. 2009; 373(9677):1808-1817.

Markmann FJ, Yeh H, Naji A, et al. Transplantation of abdominal organs. In: Townsend CM, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 18th ed. Philadelphia, Pa: Saunders Elsevier; 2008: chap 28.

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