Solid organ transplant - lung
Lung transplant is surgery to replace one or both diseased lungs with healthy lungs from a human donor.
The new lung or lungs are usually donated by someone under age 65 who is brain-dead but is still on life-support. The donor tissue must be matched as closely as possible to your tissue type to reduce the odds that your body will reject the transplanted lung.
Lungs can also be given by living donors. Two or more people are needed. Each person donates a segment (lobe) of their lung to form an entire lung for the person who is receiving it.
During lung transplant surgery, you are asleep and pain-free (under general anesthesia). A surgical cut is made in the chest. Lung transplant surgery is done with the use of a heart-lung machine, which does the work of your heart while your heart is stopped for the surgery.
After the cut is made, the major steps during lung transplant surgery include:
Sometimes heart and lung transplants are done at the same time (heart-lung transplant) if the heart is also diseased.
A lung transplant is usually the last-resort treatment for lung failure. Lung transplants may be recommended for patients under age 65 who have severe lung disease. Some examples of diseases that may require a lung transplant are:
Lung transplant may NOT be done for patients who:
The doctor may recommend against a heart transplant if there is concern that you will not be able to keep up with the many hospital and doctor's visits, tests, and medications needed to keep the new heart healthy.
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Flume PA, Mogayzel PJ Jr, Robinson KA, Rosenblatt RL, Quittell L, Marshall BC; Clinical Practice Guidelines for Pulmonary Therapies Committee; Cystic Fibrosis Foundation Pulmonary Therapies Committee. Cystic fibrosis pulmonary guidelines: Pulmonary complications: hemoptysis and pneumothorax. Am J Respir Crit Care Med. 2010; 182(3):298-306.
Kotloff RM. Lung transplantation. In: Mason RJ, Broaddus CV, Martin TR, et al. Murray & Nadel's Textbook of Respiratory Medicine. 5th ed. Philadelphia, Pa: Saunders Elsevier; 2010:chap 95.
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