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Aphthous stomatitis
Most mouth sores are cold sores (also called fever blisters), canker sores, or other irritation caused by:
Cold sores are caused by the herpes simplex virus and are very contagious. Usually, you will have tenderness, tingling, or burning before the actual sore appears. Cold sores usually begin as blisters and then crust over.
The herpes virus can live in your body for years. It only appears as a mouth sore when something triggers it, such as:
Canker sores are NOT contagious. They can appear as a single pale or yellow ulcer with a red outer ring, or as a cluster of these sores. The cause of canker sores is not clear, but may be related to:
For unknown reasons, women seem to get canker sores more often than men. This may be related to hormone changes.
Less commonly, mouth sores can be a sign of an illness, tumor, or reaction to a medication. Such illnesses can be grouped into several broad categories:
Drugs that may cause mouth sores include:
Daniels TE. Diseases of the mouth and salivary glands. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 451.
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