• Home

Home > Medical Reference > Encyclopedia (English)

Toggle: English / Spanish

Mouth sores

• Overview
• Treatment

Definition:

Various types of sores can appear anywhere within the mouth, including the inner cheeks, gums, tongue, lips, or palate.

Common Causes:

Most mouth sores are cold sores (also called fever blisters), canker sores, or other irritation caused by:

• Biting your cheek, tongue, or lip
• Chewing tobacco
• Braces
• A sharp or broken tooth or poorly fitting dentures
• Burning your mouth from hot food or drinks

Cold sores are caused by herpes simplex virus and are very contagious. Usually, you have tenderness, tingling, or burning before the actual sore appears. Herpes sores begin as blisters and then crust over.

The herpes virus can reside in your body for years, appearing as a mouth sore only when something provokes it. Such circumstances may include another illness, especially if there is a fever, stress, hormonal changes (such as menstruation), and sun exposure.

Canker sores are NOT contagious and can appear as a single pale or yellow ulcer with a red outer ring, or as a cluster of such lesions. The cause of canker sores is not entirely clear, but may be related to:

• A virus
• A temporary weakness in your immune system (for example, from cold or flu)
• Hormonal changes
• Mechanical irritation
• Stress
• Low levels of vitamin B12 or folate

For unknown reasons, women seem to get canker sores more often than men. This may be related to hormonal changes.

Less commonly, mouth sores can be a sign of an underlying illness, tumor, or reaction to a medication. Such potential illnesses can be grouped into several broad categories:

• Infection (such as hand-foot-mouth syndrome )
• Autoimmune diseases (including lupus)
• Bleeding disorders
• Malignancy (cancer)
• Immunosuppression (that is, when your immune system is weakened -- for example, if you have AIDS or are receiving medication after a transplant).

Drugs that might cause mouth sores include chemotherapeutic agents for cancer, aspirin, barbiturates (used for insomnia), gold (used for rheumatoid arthritis), penicillin, phenytoin (used for seizures), streptomycin, or sulfonamides.

References:

Mandell GL, Bennett JE, Dolin R. Principles and Practice of Infectious Diseases . 5th ed. London, UK: Churchill Livingstone, Inc; 2000.

Yeung-Yue KA. Herpes simplex viruses 1 and 2. Dermatol Clin . 2002; 20(2): 249-266.

MacDonald J. Canker sore remedies: baking soda. CMAJ . 2002; 166(7): 884.

• Review Date: 5/17/2007
• Reviewed By: Benjamin W. Van Voorhees, MD, MPH, Assistant Professor of Medicine, Pediatrics and Psychiatry, The University of Chicago, Chicago, IL. Review provided by VeriMed Healthcare Network.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is the first of its kind, requiring compliance with 53 standards of quality and accountability, verified by independent audit. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial process . A.D.A.M. is also a founding member of Hi-Ethics (www.hiethics.com) and subscribes to the principles of the Health on the Net Foundation (www.hon.ch).

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 1997-2007 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.