A Member of the University of Maryland Medical System | In Partnership with the University of Maryland School of Medicine
Swollen glands; Glands - swollen; Lymph nodes - swollen; Lymphadenopathy
Lymph nodes are found throughout your body. They are an important part of your immune system. Lymph nodes help your body recognize and fight germs, infections, and other foreign substances.
The term "swollen glands" refers to enlargement of one or more lymph nodes.
In a child, a node is considered enlarged if it is more than 1 centimeter (0.4 inch) in diameter.
See also: Lymphadenitis and lymphangitis
Common areas where the lymph nodes can be felt (with the fingers) include:
Lymph nodes can become swollen from infection, inflammatory conditions, an abscess, or cancer. Other causes of enlarged lymph nodes are rare. By far, the most common cause of swollen lymph nodes is infection.
When swelling appears suddenly and is painful, it is usually caused by injury or an infection. Enlargement that comes on gradually and painlessly may, in some cases, result from cancer or a tumor.
Infections that commonly cause swollen lymph nodes include:
Immune or autoimmune disorders that can cause swollen lymph nodes include rheumatoid arthritis and HIV.
Cancers that can often cause swollen lymph nodes include leukemia, Hodgkin's disease, or non-Hodgkin's lymphoma. However, many other cancers may also cause this problem.
Which lymph nodes are swollen depends on the type of problem and the body parts involved. Identifying the location can help determine the possible cause.
Swollen lymph nodes may also be caused by some medications (such phenytoin for seizures) or certain vaccinations (such as typhoid immunization).
Pasternack MS, Swartz MN. Lymphadenitis and lymphangitis. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2009:chap 92.
Nizet V, Jackson MA. Localized Lymphadenitis, lymphadenopathy, and lymphangitis. In: Long SS, ed. Principles and Practice of Pediatric Infectious Diseases. 3rd ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 22.
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (www.hon.ch).
© 2011 University of Maryland Medical Center (UMMC). All rights reserved.
UMMC is a member of the University of Maryland Medical System,
22 S. Greene Street, Baltimore, MD 21201. TDD: 1-800-735-2258 or 1.800.492.5538