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Dr. Syed Ashfaq Hasan’s Bio | Q&A Archive
Skeletal limb abnormalities refer to a variety of bone structure problems in the arms or legs (limbs).
Skeletal limb abnormalities are most often used to describe defects in the legs or arms that are associated with your genes or chromosomes, or that occur due to an event that happens during pregnancy.
The abnormalities are often present at birth.
Limb abnormalities can develop after birth in persons who have rickets and other diseases that affect bone structure.
Skeletal limb abnormalities may be due to:
Knobloch J, Shaughnessy Jr JD, Ruther U. Thalidomide induces limb deformities by perturbing the Bmp/Dkk1/Wnt signaling pathway. FASEB J. 2007 Feb 5; [Epub ahead of print].
Canale ST. Campbell's Operative Orthopaedics. 10th ed. St. Louis, Mo: Mosby; 2003:1043.
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