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Short stature - Treatment

Alternative Names

Idiopathic short stature; Non-growth hormone deficient short stature

Call your health care provider if:

All children should have their growth and development monitored on a regular basis.

If your child appears to be much shorter than most children his or her age (or if the growth rate has decreased or stopped), call your health care provider.

What to expect at your health care provider's office:

The health care provider will perform a physical examination. The child's height, weight, and arm and leg lengths will be measured. If the short stature appears to be a sign of some medical condition, further tests, including laboratory studies and x-rays, may be needed.

To learn more about possible causes, the health care provider will ask questions, such as:

  • Family history
    • How tall are the parents and grandparents?
    • How tall are the brothers or sisters?
    • Are other relatives less-than-average height?
    • Have any family members been diagnosed with a disorder that can cause short stature?
    • At what age did the parents start puberty?
  • Child's history
    • What was the child's birth like?
    • How is the child's diet?
    • Has the child begun to show signs of puberty?
    • At what age did puberty signs begin?
    • Has the child always been on the small side of the growth charts?
    • Was the child growing normally and then the rate of growth began to slow?
    • What other symptoms are present?
    • Is the child's short stature affecting self-image or causing any problems at school or with friends?

A bone age x-ray is often done. X-rays are usually made of the left wrist or hand. Normally, the size and shape of bones change as a person matures. These changes can be seen on an x-ray and usually follow a pattern as a child grows older. Certain causes of short stature may be present if the bones have not changed or matured as expected for the child's age.

Girls with short stature may have a karyotype done to check for certain genetic diseases, such as Turner syndrome.

Other tests may include:

  • Complete blood count
  • Other blood tests to look for liver, kidney, thyroid, and other medical problems
  • Insulin growth factor-1 (IGF-1) levels may be done for some children
  • Growth hormone stimulation test may be done for some children

Although your health care provider keeps records of height and weight from routine examinations, you may find it helpful to keep your own records. You may want to bring these records to your health care provider's attention if the growth seems slow or the child seems small.

TREATMENT

Children of short stature who are found to have a lack of growth hormone in their body will usually be treated with growth hormone injections.

Growth hormone injections are also used to treat children with Turner syndrome, Prader-Willi syndrome, chronic kidney failure, or idiopathic short stature (ISS).

Many children with short stature of unknown cause do not need growth hormone injections. Children who are more likely to receive growth hormone injections are:

  • Those who are greater than 2.25 - 2.5 SD below the average for their age and gender, or in the shortest 1.2% of children
  • Those who were born small for gestational age

Some boys with short stature who also have delayed puberty may receive certain medicines containing the male hormone, testosterone.

  • Reviewed last on: 9/13/2009
  • Neil K. Kaneshiro, MD, MHA, Clinical Assistant Professor of Pediatrics, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Cohen P, Rogol AD, Deal CL, et al. Wit JM: 2007 ISS Consensus Workshop participants. Consensus statement on the diagnosis and treatment of children with idiopathic short stature: a summary of the Growth Hormone Research Society, the Lawson Wilkins Pediatric Endocrine Society, and the European Society for Paediatric Endocrinology Workshop. J Clin Endocrinol Metab. 2008;93:4210-4217.

Parks JS, Feiner EL. Hypopituitarism. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa:Saunders Elsevier;2007:chap 558.

Collett-Solberg PF, Misra M. Drug and Therapeutics Committee of the Lawson Wilkins Pediatric Endocrine Society. The role of recombinant human insulin-like growth factor-1 in treating children with short stature. J Clin Endocrinol Metab. 2008;93:10-18.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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